One big thing you need to know about your reader: he or she typically is free to read or stop reading. That is the reader's part in this game, to follow you to the next sentence or blow you off with a shrug. This is axiomatic. It is a overarching condition that, as a writer, you must keep in mind. It is the fear and the hope that sits in the atmosphere around you. How do you hold your reader? Will the reader make it to the next sentence?